DEVELOPMENT OF BIOCOMPATIBLE LAYERS FOR DEGREE HEMOPERFUSION ACTIVATED CARBONS WITH MOLECULAR WEIGHT DIFFERENT ADDITIVES OF POLYETHYLENGLICOL IN CELLULOSE ACETATE

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Aramís Fernández

Abstract

The objective of the present work is the development of biocompatible layers with different molecular weight additives of polyethylene glycol in cellulose acetate for the coating of porous solids, specifically for activated carbons used as blood detoxifiers and named as Degree Hemoperfusion Activated Carbon. For this work, the cellulose acetate was selected as precursor material and the phase investment process and the precipitation technique by immersion for obtaining membranes. Different formulations were tested using the acetic acid as a solvent, polyethylene glycol as an additive modifier of different molecular weights (300, 400) and the water as no solvent. A methodology was established for obtaining polymeric membranes which were characterized by scanning electron microscopy. It was used a microporous activated carbon with features demanding in terms of adsorption capacity, selectivity and degree of purity for the elimination of toxic compounds in the blood in the process of coating. This process was checked with the best formulation for a time of immersion, drying and cycle number of impregnations that allowed us to obtain satisfactory results in relation to the control of the biocompatible layer within a range of 2 to 10 microns.

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How to Cite
Fernández, A. (2019) “DEVELOPMENT OF BIOCOMPATIBLE LAYERS FOR DEGREE HEMOPERFUSION ACTIVATED CARBONS WITH MOLECULAR WEIGHT DIFFERENT ADDITIVES OF POLYETHYLENGLICOL IN CELLULOSE ACETATE”, INFOMIN, 9(2), p. 33‐41. Available at: https://infomin.edicionescervantes.com/index.php/i/article/view/111 (Accessed: 13 May 2026).
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